Since you live in the South, I would suggest you do New England.
2 options or both, depending on how much you want to drive. I live on Cape Cod and that would be ideal. About 70 miles from Boston and then 50 more miles to Provincetown on the tip. Its lovely now that Spring is here and the best time of year (except for the Fall) Plymouth is on the way and you can follow the coast all the way down 3A going thru all the little towns rather than the highway RTE 3. Then go on to New Bedford, (whaling) and Fall River (Lizzie Borden of the famous axe), detour thru Newport (Astor and Vanderbilt, etc. "cottages") and so to Providence, a jewel of a college city (Brown Univ). Alternatively, drive north along the coast thru Salem (witches) and Rockport (famous art colony) and on to Portland. Maine (Home of the outlets and Winslow Homers Black Rock just outside of Portland) then up as far as Mt Desert Island's National Park and Northeast Harbor(old money summer resorts) And don't forget Boston itself with it's Museums, theaters, Boston Common and Public Garden, Swan Boats and the North End (follow the Freedom Trail for historical sites). Enjoy!!