I have the lowest screen resolution - 800x600. Before that, the computer was set
to the highest, as many are right from the factory, and although I could increase the font via the "view" feature, the largest font was still ridiculously small. After asking dozens of people (the tech people were no help), one optometrist out of several, whom I called out of the blue from the phone book, happened to be computer-savvy, and told me to lower the resolution and how to do it. Luckily, it's easy. Well, needless to say, he's now my optometrist. Not only is he a great guy, but an excellent doctor!
Edited to add: Dawn, I can't get mine as low as 640 x 480.